Discovery of dual S-RBD/NRP1-targeting peptides: structure-based virtual screening, synthesis, biological evaluation, and molecular dynamics simulation studies

Both receptor-binding domain in spike protein (S-RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and human neuropilin-1 (NRP1) are important in the virus entry, and their concomitant inhibition may become a potential strategy against the SARS-CoV-2 infection. Herein, five novel...

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Main Authors: Chunfang Hu (Author), Ting Guo (Author), Yunting Zou (Author), Junyi Gao (Author), Yi Gao (Author), Miaomiao Niu (Author), Yang Xia (Author), Xiaozhou Shen (Author), Jindong Li (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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