Placental CD4+ T cells from preeclamptic patients cause autoantibodies to the angiotensin II type I receptor and hypertension in a pregnant rat model of preeclampsia

• Κύριοι συγγραφείς: Kristin E. Reeve (Συγγραφέας), Evangeline Deer (Συγγραφέας), Lorena M. Amaral (Συγγραφέας), Denise C. Cornelius (Συγγραφέας), Owen Herrock (Συγγραφέας), Ashlyn C. Harmon (Συγγραφέας), Nathan Campbell (Συγγραφέας), Sarah Fitzgerald (Συγγραφέας), Tarek Ibrahim (Συγγραφέας), Gerd Wallukat (Συγγραφέας), Ralf Dechend (Συγγραφέας), Babbette LaMarca (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Open Exploration Publishing Inc., 2022-02-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Aim: Preeclampsia (PE) is a hypertensive disorder of pregnancy associated with activated CD4+ T cells and autoantibodies to angiotensin II type 1 receptor (AT1-AA). We have previously shown that CD4+ T cells isolated from women with PE cause hypertension, increased tumor necrosis factor alpha (TNF-α...