Association between polymorphisms in the GRIN1 gene 5' regulatory region and schizophrenia in a northern Han Chinese population and haplotype effects on protein expression in vitro

• Main Authors: Yong-ping Liu (Author), Mei Ding (Author), Xi-cen Zhang (Author), Yi Liu (Author), Jin-feng Xuan (Author), Jia-xin Xing (Author), Xi Xia (Author), Jun Yao (Author), Bao-jie Wang (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Schizophrenia is a severe neurodevelopmental disorder with a complex genetic and environmental etiology. Abnormal glutamate ionotropic N-methyl-D-aspartate receptor (NMDA) type subunit 1 (NR1) may be a potential cause of schizophrenia. Methods We conducted a case-control study to...