Genome-Wide Association Study-Guided Exome Rare Variant Burden Analysis Identifies IL1R1 and CD3E as Potential Autoimmunity Risk Genes for Celiac Disease

• Hoofdauteurs: Haifa Mansour (Auteur), Babajan Banaganapalli (Auteur), Khalidah Khalid Nasser (Auteur), Jumana Yousuf Al-Aama (Auteur), Noor Ahmad Shaik (Auteur), Omar Ibrahim Saadah (Auteur), Ramu Elango (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Celiac disease (CeD) is a multifactorial autoimmune enteropathy characterized by the overactivation of the immune system in response to dietary gluten. The molecular etiology of CeD is still not well-understood. Therefore, this study aims to identify potential candidate genes involved in CeD pathoge...