Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.

• Principais autores: Pavla Fajtová (Autor), Saša Štefanić (Autor), Martin Hradilek (Autor), Jan Dvořák (Autor), Jiří Vondrášek (Autor), Adéla Jílková (Autor), Lenka Ulrychová (Autor), James H McKerrow (Autor), Conor R Caffrey (Autor), Michael Mareš (Autor), Martin Horn (Autor)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Blood flukes of the genus Schistosoma cause schistosomiasis, a parasitic disease that infects over 240 million people worldwide, and for which there is a need to identify new targets for chemotherapeutic interventions. Our research is focused on Schistosoma mansoni prolyl oligopeptidase (SmPOP) from...