Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.

• Main Authors: Pavla Fajtová (Author), Saša Štefanić (Author), Martin Hradilek (Author), Jan Dvořák (Author), Jiří Vondrášek (Author), Adéla Jílková (Author), Lenka Ulrychová (Author), James H McKerrow (Author), Conor R Caffrey (Author), Michael Mareš (Author), Martin Horn (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Blood flukes of the genus Schistosoma cause schistosomiasis, a parasitic disease that infects over 240 million people worldwide, and for which there is a need to identify new targets for chemotherapeutic interventions. Our research is focused on Schistosoma mansoni prolyl oligopeptidase (SmPOP) from...