5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages

• Main Authors: Panqiao Liang (Author), Linxin Wang (Author), Sushan Yang (Author), Xiping Pan (Author), Jiashun Li (Author), Yuehan Zhang (Author), Yueyun Liang (Author), Jing Li (Author), Beixian Zhou (Author)
• Formato: Livro
• Publicado em: BMC, 2022-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Acute lung injury (ALI) arises from sepsis or bacterial infection, which are life-threatening respiratory disorders that cause the leading cause of death worldwide. 5-Methoxyflavone, a methylated flavonoid, is gaining increased attention for its various health benefits. In the cu...