The Invisible Threat of Non-steroidal Anti-inflammatory Drugs for Kidneys

• Egile Nagusiak: Stéphanie Clavé (Egilea), Caroline Rousset-Rouvière (Egilea), Laurent Daniel (Egilea), Michel Tsimaratos (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are often used as analgesic and antipyretic drugs. Nephrotoxicity is a common side effect and leads in 1-5% of pediatric cases to acute kidney injury (AKI). The nephrotoxic effects of NSAIDs arise mainly from two pathological mechanisms: (1)...