Bioimaging Nucleic-Acid Aptamers with Different Specificities in Human Glioblastoma Tissues Highlights Tumoral Heterogeneity

• Main Authors: Elisabete Cruz Da Silva (Author), Sophie Foppolo (Author), Benoît Lhermitte (Author), Marina Ingremeau (Author), Hélène Justiniano (Author), Lorraine Klein (Author), Marie-Pierre Chenard (Author), Romain Vauchelles (Author), Basma Abdallah (Author), Maxime Lehmann (Author), Nelly Etienne-Selloum (Author), Monique Dontenwill (Author), Laurence Choulier (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nucleic-acid aptamers are of strong interest for diagnosis and therapy. Compared with antibodies, they are smaller, stable upon variations in temperature, easy to modify, and have higher tissue-penetration abilities. However, they have been little described as detection probes in histology studies o...