Rapid discovery of a novel "green" and natural GST inhibitor for sensitizing hepatocellular carcinoma to Cisplatin by visual screening strategy

• Main Authors: Linxi Mao (Author), Yan Qin (Author), Jialong Fan (Author), Wei Yang (Author), Bin Li (Author), Liang Cao (Author), Liqin Yuan (Author), Mengyun Wang (Author), Bin Liu (Author), Wei Wang (Author)
• Format: Book
• Published: Elsevier, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Over-expression of glutathione S-transferase (GST) can promote Cisplatin resistance in hepatocellular carcinoma (HCC) treatment. Hence, inhibiting GST is an attractive strategy to improve Cisplatin sensitivity in HCC therapy. Although several synthesized GST inhibitors have been developed, the side...