Ionotropic purinergic receptor 7 (P2X7) channel structure and pharmacology provides insight regarding non-nucleotide agonism

ABSTRACTP2X7 is a member of the Ionotropic Purinergic Receptor (P2X) family. The P2X family of receptors is composed of seven (P2X1-7), ligand-gated, nonselective cation channels. Changes in P2X expression have been reported in multiple disease models. P2Xs have large complex extracellular domains t...

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Hlavní autoři: Rua'a Al-Aqtash (Autor), Daniel M. Collier (Autor)
Médium: Kniha
Vydáno: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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