Polymorphisms rs231775 and rs5742909 CTLA-4 gene and their associative relations with chronic HBV infection in children

• Main Authors: F. I. Inoyatova (Author), G. Z. Inogamova (Author), F. G. Abdullaevа (Author), N. K. Valievа (Author), N. A. Ikramova (Author), H. M. Kadyrhodzhaevа (Author), A. Kh. Akhmedovа (Author)
• Format: Book
• Published: LLC "Diagnostics and Vaccines", 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study of the genetic polymorphism rs231775 (+ 49A > G) and rs5742909 (+ 3 18С > Т) of the CTLA-4 gene in 100 children with chronic HBV infection revealed associations only with the carriage of the + 49A/ G polymorphic variant. Moreover, the carriage of the G allele in the homozygous mutant...