Supplemental Treatment for Huntington's Disease with miR-132 that Is Deficient in Huntington's Disease Brain

• Main Authors: Masashi Fukuoka (Author), Masaki Takahashi (Author), Hiromi Fujita (Author), Tomoko Chiyo (Author), H. Akiko Popiel (Author), Shoko Watanabe (Author), Hirokazu Furuya (Author), Miho Murata (Author), Keiji Wada (Author), Takashi Okada (Author), Yoshitaka Nagai (Author), Hirohiko Hohjoh (Author)
• Format: Book
• Published: Elsevier, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Huntington's disease (HD) is an intractable neurodegenerative disorder caused by mutant Huntingtin (HTT) proteins that adversely affect various biomolecules and genes. MicroRNAs (miRNAs), which are functional small non-coding RNAs, are also affected by mutant HTT proteins. Here, we show amelior...