CYP and SXR gene polymorphisms influence in opposite ways acute rejection rate in pediatric patients with renal transplant

• Asıl Yazarlar: Stefano Turolo (Yazar), Alberto Edefonti (Yazar), Luciana Ghio (Yazar), Sara Testa (Yazar), William Morello (Yazar), Giovanni Montini (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2020-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background We evaluated the role of CYP3A5, ABCB1 and SXR gene polymorphisms in the occurrence of acute kidney rejection in a cohort of pediatric renal transplant recipients. Methods Forty-nine patients were genotyped for CYP3A5, ABCB1 and SXR polymorphisms and evaluated with tacrolimus thr...