CYP and SXR gene polymorphisms influence in opposite ways acute rejection rate in pediatric patients with renal transplant

• Główni autorzy: Stefano Turolo (Autor), Alberto Edefonti (Autor), Luciana Ghio (Autor), Sara Testa (Autor), William Morello (Autor), Giovanni Montini (Autor)
• Format: Książka
• Wydane: BMC, 2020-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background We evaluated the role of CYP3A5, ABCB1 and SXR gene polymorphisms in the occurrence of acute kidney rejection in a cohort of pediatric renal transplant recipients. Methods Forty-nine patients were genotyped for CYP3A5, ABCB1 and SXR polymorphisms and evaluated with tacrolimus thr...