Intradermal Delivery of Synthetic mRNA Using Hollow Microneedles for Efficient and Rapid Production of Exogenous Proteins in Skin

• मुख्य लेखकों: Sonia Golombek (लेखक), Martin Pilz (लेखक), Heidrun Steinle (लेखक), Efrat Kochba (लेखक), Yotam Levin (लेखक), Dominique Lunter (लेखक), Christian Schlensak (लेखक), Hans Peter Wendel (लेखक), Meltem Avci-Adali (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2018-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In recent years, synthetic mRNA-based applications to produce desired exogenous proteins in cells have been gaining importance. However, systemic delivery of synthetic mRNA can result in unspecific uptake into undesired cells or organs and, thereby, fail to target desired cells. Thus, local and targ...