Therapeutic drug monitoring of tacrolimus in pancreas transplantation at São Lucas Hospital Monitoramento terapêutico de tacrolimus em transplante de pâncreas no Hospital São Lucas

• Main Authors: Luciana Mello de Oliveira (Author), Ana Lígia Bender (Author), Moacir A. Traesel (Author), Leonardo Kroth (Author), Marcelo J. Hartmann (Author), Salvador Gullo Neto (Author), David Saitovitch (Author), Flavia Valladão Thiesen (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2007-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tacrolimus (FK 506), a potent immunosuppressive drug used in prevention and treatment of rejection of transplanted organs, exhibits efficacy related to its blood levels and has a narrow therapeutic index. These factors require frequent monitoring of patients blood levels, in attempt to adjust the do...