Dual Function of Wnt Signaling during Neuronal Differentiation of Mouse Embryonic Stem Cells
Activation of Wnt signaling enhances self-renewal of mouse embryonic and neural stem/progenitor cells. In contrast, undifferentiated ES cells show a very low level of endogenous Wnt signaling, and ectopic activation of Wnt signaling has been shown to block neuronal differentiation. Therefore, it rem...
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Main Authors: | , , , , , |
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Format: | Book |
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Hindawi Limited,
2015-01-01T00:00:00Z.
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A1234.567 |
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