Agonistic anti-NKG2D antibody structure reveals unique stoichiometry and epitope compared to natural ligands

• Main Authors: Daniel Fallon (Author), Ching-Shin Huang (Author), Jingya Ma (Author), Christopher Morgan (Author), Zhaohui Sunny Zhou (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Natural killer (NK) cells are effector cells of the innate immune system that distinguish between healthy and abnormal cells through activating and inhibitory receptor signaling. NKG2D, a homodimeric activating receptor expressed on NK cells, recognizes a diverse class of stress ligands expressed by...