Pharmacokinetic/Toxicity Properties of the New Anti-Staphylococcal Lead Compound SK-03-92

Pharmacokinetic/Toxicity Properties of the New Anti-Staphylococcal Lead Compound SK-03-92

Because of the potential of a new anti-staphylococcal lead compound SK-03-92 as a topical antibiotic, a patch, or an orally active drug, we sought to determine its safety profile and oral bioavailability. SK-03-92 had a high IC50 (125 μg/mL) in vitro against several mammalian cell lines, and mice in...

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Main Authors: William R. Schwan (Author), Jill M. Kolesar (Author), M. Shahjahan Kabir (Author), Edmund J. Elder (Author), Jeffrey B. Williams (Author), Rachel Minerath (Author), James M. Cook (Author), Christopher M. Witzigmann (Author), Aaron Monte (Author), Tricia Flaherty (Author)
Format: Book
Published: MDPI AG, 2015-11-01T00:00:00Z.
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3rd Floor Main Library

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