ClickArr: a novel, high-throughput assay for evaluating β-arrestin isoform recruitment
Background: Modern methods for quantifying signaling bias at G protein-coupled receptors (GPCRs) rely on using a single β-arrestin isoform. However, it is increasingly appreciated that the two β-arrestin isoforms have unique roles, requiring the ability to assess β-arrestin isoform preference. Thus,...
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Frontiers Media S.A.,
2023-11-01T00:00:00Z.
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