TIMP‐1‐expressing breast tumor spheroids for the evaluation of drug penetration and efficacy

• Main Authors: In Yeong Bae (Author), Wooshik Choi (Author), Seung Ja Oh (Author), Chansoo Kim (Author), Sang‐Heon Kim (Author)
• 格式: 圖書
• 出版: Wiley, 2022-05-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Abstract Abundance of stromal cells and extracellular matrix (ECM) is observed in breast cancer, acting as a barrier for drug penetration and presenting a key issue for developing efficient therapeutics. In this study, we aimed to develop a three‐dimensional (3D) multicellular tumor model comprising...