Cytochrome P450 1A2 Is Incapable of Oxidizing Bilirubin Under Physiological Conditions
Background: Bilirubin (BR) is metabolized mainly by uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1) through glucuronidation in the liver. Some studies have shown that several subtypes of cytochrome P450 (CYP) enzymes, including CYP1A2, are upregulated by inducers and proposed to be al...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2019-10-01T00:00:00Z.
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