Wilson disease, ABCC2 c.3972C > T polymorphism and primary liver cancers: suggestions from a familial cluster

• Главные авторы: Giovanni Brandi (Автор), Alessandro Rizzo (Автор), Marzia Deserti (Автор), Valeria Relli (Автор), Valentina Indio (Автор), Sofia Bin (Автор), Milena Pariali (Автор), Andrea Palloni (Автор), Stefania De Lorenzo (Автор), Francesco Tovoli (Автор), Simona Tavolari (Автор)
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• Опубликовано: BMC, 2020-11-01T00:00:00Z.
• Предметы: article
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Abstract Background Polymorphisms in genes modulating xenobiotics metabolism, in particular the ABCC2 c.3972C > T single nucleotide polymorphism (SNP) at exon 28, have been suggested to increase primary liver cancer (PLC) risk. Conversely, the occurrence of PLCs in Wilson disease patients is a ra...