RNA editing regulates glutamatergic synapses in the frontal cortex of a molecular subtype of Amyotrophic Lateral Sclerosis

• Главные авторы: Korina Karagianni (Автор), Dimitra Dafou (Автор), Konstantinos Xanthopoulos (Автор), Theodoros Sklaviadis (Автор), Eirini Kanata (Автор)
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• Опубликовано: BMC, 2024-07-01T00:00:00Z.
• Предметы: article
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Abstract Background Amyotrophic Lateral Sclerosis (ALS) is a highly heterogenous neurodegenerative disorder that primarily affects upper and lower motor neurons, affecting additional cell types and brain regions. Underlying molecular mechanisms are still elusive, in part due to disease heterogeneity...