Comprehensive Assessment of Pharmacokinetics, Pharmacodynamics, and Tolerability of Ligelizumab in Healthy Volunteers and Patients with Chronic Spontaneous Urticaria to Optimize Its Subcutaneous Delivery System

Comprehensive Assessment of Pharmacokinetics, Pharmacodynamics, and Tolerability of Ligelizumab in Healthy Volunteers and Patients with Chronic Spontaneous Urticaria to Optimize Its Subcutaneous Delivery System

Ligelizumab is a highly potent, humanized IgG1, anti-IgE monoclonal antibody. To explore its optimal subcutaneous delivery, the pharmacokinetics (PK), pharmacodynamics (PD), and tolerability of ligelizumab from two Phase 1 studies in healthy volunteers (HVs) and four Phase 2 and 3 studies in patient...

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Main Authors: Yan Ji (Author), Claudio Calonder (Author), Tiina Kirsilä (Author), Alis Burciu (Author), Matjaz Tisu (Author), Yolandi Joubert (Author), Nathalie Laurent (Author), Eva Hua (Author), Manmath Patekar (Author), Anton Drollmann (Author), Ralph Woessner (Author)
Format: Book
Published: MDPI AG, 2023-09-01T00:00:00Z.
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