Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myocardial Infarction

• Hoofdauteurs: Enrique Gallego-Colon (Auteur), Robert D. Sampson (Auteur), Susanne Sattler (Auteur), Michael D. Schneider (Auteur), Nadia Rosenthal (Auteur), Joanne Tonkin (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2015-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Strategies to limit damage and improve repair after myocardial infarct remain a major therapeutic goal in cardiology. Our previous studies have shown that constitutive expression of a locally acting insulin-like growth factor-1 Ea (IGF-1Ea) propeptide promotes functional restoration after cardiac in...