Kai-Xin-San protects against mitochondrial dysfunction in Alzheimer's disease through SIRT3/NLRP3 pathway

• Main Authors: ShiJie Su (Author), Gongcan Chen (Author), Minghuang Gao (Author), Guangcheng Zhong (Author), Zerong Zhang (Author), Dongyun Wei (Author), Xue Luo (Author), Qi Wang (Author)
• Format: Book
• Published: BMC, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Kai-Xin-San (KXS) has been reported to have a good curative impact on dementia. The purpose of the study was to determine whether KXS might ameliorate cognitive deficits in APP/PS1 mice and to evaluate its neuroprotective mechanism. Methods APP/PS1 mice were employed as an AD ani...