MicroRNA-dependent inhibition of WEE1 controls cancer stem-like characteristics and malignant behavior in ovarian cancer

• Main Authors: Jin Gu Cho (Author), Sung-wook Kim (Author), Aram Lee (Author), Ha-neul Jeong (Author), Eunsik Yun (Author), Jihea Choi (Author), Su Jin Jeong (Author), Woochul Chang (Author), Sumin Oh (Author), Kyung Hyun Yoo (Author), Jung Bok Lee (Author), Sukjoon Yoon (Author), Myeong-Sok Lee (Author), Jong Hoon Park (Author), Min Hyung Jung (Author), So-Woon Kim (Author), Ki Hyung Kim (Author), Dong Soo Suh (Author), Kyung Un Choi (Author), Jungmin Choi (Author), Jongmin Kim (Author), Byung Su Kwon (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer stem-like cells (CSCs) have been suggested to be responsible for chemoresistance and tumor recurrence owing to their self-renewal capacity and differentiation potential. Although WEE1 is a strong candidate target for anticancer therapies, its role in ovarian CSCs is yet to be elucidated. Here...