(+)/(−)-Gerbeloid A, a pair of unprecedented coumarin-based polycyclic meroterpenoid enantiomers from Gerbera piloselloides: Structural elucidation, semi-synthesis, and lipid-lowering activity

• Main Authors: Chenxu Zhao (Author), Jingrong Li (Author), Yue Hu (Author), Lingyu Li (Author), Meng Yu (Author), Yunfeng Huang (Author), Tao Zhang (Author), Hai Shang (Author), Zhongmei Zou (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A pair of coumarin-based polycyclic meroterpenoid enantiomers (+)/(−)-gerbeloid A [(+)-1a and (−)-1b] were isolated from the medicinal plant Gerbera piloselloides, which have a unique caged oxatricyclo [4.2.2.03,8] decene scaffold. Their planar and three-dimensional structures were exhaustively char...