Discovery of novel favipiravir derivatives with improved pharmacokinetic properties as anti-SFTSV agents

• Main Authors: Xiaomeng He (Author), Fan Wu (Author), Wei Li (Author), Runze Zhang (Author), Ruiyang Sun (Author), Zhihong Hu (Author), Wu Zhong (Author), Manli Wang (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Favipiravir is a nucleobase analogue that exhibits antiviral activities against a variety of RNA viruses. Due to the lack of antivirals to combat SFTS, an emerging tickborne epidemic caused by a RNA virus belonging to the Phenuividae family within Bunyavirales, Favipiravir has been put brand new att...