Enantioselective analysis of fluoxetine in pharmaceutical formulations by capillary zone electrophoresis

• Main Authors: Melania Cârcu-Dobrin (Author), Monica Budău (Author), Gabriel Hancu (Author), Laszlo Gagyi (Author), Aura Rusu (Author), Hajnal Kelemen (Author)
• Format: Book
• Published: Elsevier, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fluoxetine is an antidepressant, a selective serotonin reuptake inhibitor (SSRI) used primarily in the treatment of major depression, panic disorder and obsessive compulsive disorder. Chiral separation of racemic fluoxetine is necessary due to its enantioselective metabolism. In order to develop a s...