The use of mouse models to understand and improve cognitive deficits in Down syndrome

• मुख्य लेखकों: Ishita Das (लेखक), Roger H. Reeves (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2011-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Remarkable advances have been made in recent years towards therapeutics for cognitive impairment in individuals with Down syndrome (DS) by using mouse models. In this review, we briefly describe the phenotypes of mouse models that represent outcome targets for drug testing, the behavioral tests used...