Refined Baohe formula protects against 5-fluorouracil-induced intestinal mucositis by modulating AKT pathway in CT-26 tumor-bearing mice

• Main Authors: Liya Liu (Author), Youqin Chen (Author), Ying Cheng (Author), Meizhu Wu (Author), Jie Li (Author), Jiapeng Li (Author), Thomas Joseph Sferra (Author), Senthilkumar Sankararaman (Author), Jianfeng Chu (Author), Aling Shen (Author), Jun Peng (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: 5-Fluorouracil (5-FU) is one of the most commonly prescribed anticancer agents. However, intestinal mucositis is a well-known adverse event, which limits its therapeutic use. Refined Baohe formula (RBF) is derived from Baohe Pills with a potent gastrointestinal protective effect. However...