Cytotoxic and Pro-Apoptotic Effects of a Sub-Toxic Concentration of Fluvastatin on OVCAR3 Ovarian Cancer Cells After its Optimized Formulation to Melittin Nano-Conjugates

• Main Authors: Shaimaa M. Badr-Eldin (Author), Nabil A. Alhakamy (Author), Usama A. Fahmy (Author), Osama A. A. Ahmed (Author), Hani Z. Asfour (Author), Abdulhamid A. Althagafi (Author), Hibah M. Aldawsari (Author), Waleed Y. Rizg (Author), Wael A. Mahdi (Author), Adel F. Alghaith (Author), Sultan Alshehri (Author), Filippo Caraci (Author), Giuseppe Caruso (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fluvastatin (FLV) is a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor often used to lower total and low-density lipoprotein (LDL) cholesterol and for the prevention of adverse cardiovascular events. This drug as well as melittin (MEL), the major component of honeybee venom (Apis mell...