Development of Analytical Quality by Design Compliant Chaotropic Chromatography Method for Ziprasidone and Its Five Impurities Determination

• Κύριοι συγγραφείς: Milena Rmandić (Συγγραφέας), Đorđe Vasilić (Συγγραφέας), Marija Rašević (Συγγραφέας), Mira Zečević (Συγγραφέας), Biljana Otašević (Συγγραφέας), Ana Protić (Συγγραφέας), Anđelija Malenović (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2023-09-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

In this study, an AQbD-compliant chaotropic chromatography method for ziprasidone and the determination of its five impurities was developed. The influence of critical method parameters (initial and final methanol fraction in the mobile phase, gradient duration) on the set of selected critical metho...