Transcriptional blood signatures for active and amphotericin B treated visceral leishmaniasis in India.

• Main Authors: Michaela Fakiola (Author), Om Prakash Singh (Author), Genevieve Syn (Author), Toolika Singh (Author), Bhawana Singh (Author), Jaya Chakravarty (Author), Shyam Sundar (Author), Jenefer M Blackwell (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amphotericin B provides improved therapy for visceral leishmaniasis (VL) caused by Leishmania donovani, with single dose liposomal-encapsulated Ambisome providing the best cure rates. The VL elimination program aims to reduce the incidence rate in the Indian subcontinent to <1/10,000 population/y...