N-Methyl-D-aspartate Induces Phosphorylation of cAMP Response Element (CRE)-Binding Protein and Increases DNA-Binding Activity of CRE in Rat Retina

• Main Authors: Kazuyuki Isenoumi (Author), Toshio Kumai (Author), Yasushi Kitaoka (Author), Masamitsu Motoki (Author), Yuka Kitaoka (Author), Kohei Kuribayashi (Author), Yasunari Munemasa (Author), Jiro Kogo (Author), Shinichi Kobayashi (Author), Satoki Ueno (Author)
• Format: Book
• Published: Elsevier, 2004-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to investigate whether an excitotoxic concentration of N-methyl-D-aspartate (NMDA) increases the expression of the phosphorylated cAMP response element-binding protein (p-CREB) and the DNA-binding activity of the cAMP response element (CRE) in rat retina. Intravitreal injec...