A mutual regulatory loop between miR-155 and SOCS1 influences renal inflammation and diabetic kidney disease

• Main Authors: Ignacio Prieto (Author), María Kavanagh (Author), Luna Jimenez-Castilla (Author), Marisa Pardines (Author), Iolanda Lazaro (Author), Isabel Herrero del Real (Author), Monica Flores-Muñoz (Author), Jesus Egido (Author), Oscar Lopez-Franco (Author), Carmen Gomez-Guerrero (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic kidney disease (DKD) is a common microvascular complication of diabetes, a global health issue. Hyperglycemia, in concert with cytokines, activates the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway to induce inflammation and oxidative stress contributing...