Efficient drug and gene delivery to liver fibrosis: rationale, recent advances, and perspectives

• Egile Nagusiak: Somayeh Mahdinloo (Egilea), Seyed Hossein Kiaie (Egilea), Ala Amiri (Egilea), Salar Hemmati (Egilea), Hadi Valizadeh (Egilea), Parvin Zakeri-Milani (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2020-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Liver fibrosis results from chronic damages together with an accumulation of extracellular matrix, and no specific medical therapy is approved for that until now. Due to liver metabolic capacity for drugs, the fragility of drugs, and the presence of insurmountable physiological obstacles in the way...