Treating Pulmonary Fibrosis with Non-Viral Gene Therapy: From Bench to Bedside

• Main Authors: Teng Huang (Author), Jia Gao (Author), Long Cai (Author), Hao Xie (Author), Yuhan Wang (Author), Yi Wang (Author), Qing Zhou (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by irreversible lung scarring, which achieves almost 80% five-year mortality rate. Undeniably, commercially available pharmaceuticals, such as pirfenidone and nintedanib, exhibit certain effects on improving the...