4-OI Attenuates Carbon Tetrachloride-Induced Hepatic Injury via Regulating Oxidative Stress and the Inflammatory Response

• Главные авторы: Ruidong Li (Автор), Wenchang Yang (Автор), Yuping Yin (Автор), Xianxiong Ma (Автор), Peng Zhang (Автор), Kaixiong Tao (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Предметы: article
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The liver is an important metabolic organ, and acute liver injury (ALI) is potentially lethal. Itaconate, a metabolic intermediate from the tricarboxylic acid cycle, showed emerging anti-oxidative and anti-inflammation properties, and an accumulating protective effect in multiple diseases, but its r...