Nanoscale metal-organic frameworks for the delivery of nucleic acids to cancer cells

• Main Authors: Xue Li (Author), Morgan Chandler (Author), Yelixza I. Avila (Author), Sandra I. Arroyo-Becker (Author), Gilles Patriarche (Author), Antonio Vargas-Berenguel (Author), Juan M. Casas-Solvas (Author), Kirill A. Afonin (Author), Ruxandra Gref (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Therapeutic nucleic acids (TNAs) are gaining increasing interest in the treatment of severe diseases including viral infections, inherited disorders, and cancers. However, the efficacy of intracellularly functioning TNAs is also reliant upon their delivery into the cellular environment, as unmodifie...