Impact of Small Molecules Immunosuppressants on P-Glycoprotein Activity and T-cell Function

• Główni autorzy: Inés Llaudó (Autor), Linda Cassis (Autor), Joan Torras (Autor), Oriol Bestard (Autor), Marcel·la Franquesa (Autor), Josep M. Cruzado (Autor), Gema Cerezo (Autor), Esther Castaño (Autor), Jordi Petriz (Autor), Immaculada Herrero-Fresneda (Autor), Josep M. Grinyó (Autor), Núria Lloberas (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2012-07-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Purpose. P-glycoprotein (Pgp) is a member of the ABC-transporter family that transports substances across cellular membranes acting as an efflux pump extruding drugs out of the cells. Pgp plays a key role on the pharmacokinetics of several drugs. Herein, we have studied the effects of immunosuppress...