Surface Modification of Biodegradable Microparticles with the Novel Host-Derived Immunostimulant CPDI-02 Significantly Increases Short-Term and Long-Term Mucosal and Systemic Antibodies against Encapsulated Protein Antigen in Young Naïve Mice after Respiratory Immunization

• Hauptverfasser: Jacob E. Parriott (Verfasst von), Jason P. Stewart (Verfasst von), D. David Smith (Verfasst von), Stephen M. Curran (Verfasst von), Christopher D. Bauer (Verfasst von), Todd A. Wyatt (Verfasst von), Joy A. Phillips (Verfasst von), Elizabeth Lyden (Verfasst von), Geoffrey M. Thiele (Verfasst von), Joseph A. Vetro (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-09-01T00:00:00Z.
• Schlagworte: article
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Generating long-lived mucosal and systemic antibodies through respiratory immunization with protective antigens encapsulated in nanoscale biodegradable particles could potentially decrease or eliminate the incidence of many infectious diseases, but requires the incorporation of a suitable mucosal im...