In Vivo Sub-chronic Treatment with Dichlorvos in Young Rats Promotes Synaptic Plasticity and Learning by a Mechanism that Involves Acylpeptide Hydrolase Instead of Acetylcholinesterase Inhibition. Correlation with Endogenous β-Amyloid Levels

• Asıl Yazarlar: Gonzalo García-Rojo (Yazar), Fernando Gámiz (Yazar), Estíbaliz Ampuero (Yazar), Daniel Rojas-Espina (Yazar), Rodrigo Sandoval (Yazar), Carlos Rozas (Yazar), Bernardo Morales (Yazar), Ursula Wyneken (Yazar), Floria Pancetti (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2017-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Acylpeptide hydrolase (APEH) is a serine hydrolase that displays two catalytic activities, acting both as an exopeptidase toward short N-acylated peptides and as an endopeptidase toward oxidized peptides or proteins. It has been demonstrated that this enzyme can degrade monomers, dimers, and trimers...