HNPCC: Six new pathogenic mutations

• Main Authors: Epplen Joerg T (Author), Hahn Stephan A (Author), Brasch Frank E (Author), Vieland Judith (Author), Kunstmann Erdmute (Author), Schulmann Karsten (Author), Schmiegel Wolff (Author)
• Format: Book
• Published: BMC, 2004-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant disease with a high risk for colorectal and endometrial cancer caused by germline mutations in DNA mismatch-repair genes (MMR). HNPCC accounts for approximat...