Application of Transthoracic Echocardiography for Cardiac Safety Evaluation in the Clinical Development Process of Vaccines Against Streptococcus pyogenes

• Main Authors: Usman Nakakana (Author), Alimamy Serry-Bangura (Author), Bassey Effiom Edem (Author), Pietro Tessitore (Author), Leonardo Di Cesare (Author), Danilo Gomes Moriel (Author), Audino Podda (Author), Iris Sarah De Ryck (Author), Ashwani Kumar Arora (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Superficial infections with Streptococcus pyogenes (Strep A), pharyngitis and impetigo can induce acute rheumatic fever, an autoimmune sequela manifesting mostly with arthritis and rheumatic carditis. Valvular heart damage can persist or advance following repeated episodes of acute rheumati...