Leukemia development initiated by deletion of RBP-J: mouse strain, deletion efficiency and cell of origin
Conditional deletion of RBP-J, the major transcriptional effector of Notch signaling, specifically within renin-expressing cells leads to the development of B-cell leukemia. However, the influence of contributing factors such as mouse strain, cell of origin and Cre recombinase copy number are unknow...
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Format: | Book |
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The Company of Biologists,
2018-12-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |