Downregulation of hepatic lipopolysaccharide binding protein improves lipogenesis-induced liver lipid accumulation

• Glavni autori: Jessica Latorre (Autor), Ramon Díaz-Trelles (Autor), Ferran Comas (Autor), Aleix Gavaldà-Navarro (Autor), Edward Milbank (Autor), Nathalia Dragano (Autor), Samantha Morón-Ros (Autor), Rajesh Mukthavaram (Autor), Francisco Ortega (Autor), Anna Castells-Nobau (Autor), Núria Oliveras-Cañellas (Autor), Wifredo Ricart (Autor), Priya P. Karmali (Autor), Kiyoshi Tachikawa (Autor), Pad Chivukula (Autor), Francesc Villarroya (Autor), Miguel López (Autor), Marta Giralt (Autor), José Manuel Fernández-Real (Autor), José María Moreno-Navarrete (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2022-09-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Circulating lipopolysaccharide-binding protein (LBP) is increased in individuals with liver steatosis. We aimed to evaluate the possible impact of liver LBP downregulation using lipid nanoparticle-containing chemically modified LBP small interfering RNA (siRNA) (LNP-Lbp UNA-siRNA) on the development...