Blueprint for antibody biologics developability

• Main Authors: Carl Mieczkowski (Author), Xuejin Zhang (Author), Dana Lee (Author), Khanh Nguyen (Author), Wei Lv (Author), Yanling Wang (Author), Yue Zhang (Author), Jackie Way (Author), Jean-Michel Gries (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTLarge-molecule antibody biologics have revolutionized medicine owing to their superior target specificity, pharmacokinetic and pharmacodynamic properties, safety and toxicity profiles, and amenability to versatile engineering. In this review, we focus on preclinical antibody developability,...