Mechanistic Multiscale Pharmacokinetic Model for the Anticancer Drug 2',2'‐difluorodeoxycytidine (Gemcitabine) in Pancreatic Cancer

The aim of this work is to build a mechanistic multiscale pharmacokinetic model for the anticancer drug 2',2'‐difluorodeoxycytidine (gemcitabine, dFdC), able to describe the concentrations of dFdC metabolites in the pancreatic tumor tissue in dependence of physiological and genetic patient...

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Main Authors: Maria Garcia‐Cremades (Author), Nicola Melillo (Author), Iñaki F. Troconiz (Author), Paolo Magni (Author)
Format: Book
Published: Wiley, 2020-05-01T00:00:00Z.
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3rd Floor Main Library

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